Our Research

Conducting rigorous, evidence-based research to advance understanding of cannabis and cannabinoids for therapeutic applications.

Research Focus Areas

Our interdisciplinary approach spans multiple domains of cannabis science.

Cannabinoid Science

Investigating the molecular mechanisms, pharmacology, and biochemistry of cannabinoids and the endocannabinoid system.

Medical Applications

Clinical trials and studies examining therapeutic potential for pain, epilepsy, mental health, and other conditions.

Policy & Regulation

Evidence-based analysis of cannabis policies, regulations, and their public health impacts worldwide.

Safety & Public Health

Research on cannabis use patterns, safety profiles, dosing guidelines, and harm reduction strategies.

Featured Research Projects

Current studies advancing cannabinoid science and medicine.

Cannabinoids in Chronic Pain Management
OngoingClinical Trial

Cannabinoids in Chronic Pain Management

Multi-center randomized controlled trial examining the efficacy of various cannabinoid formulations in treating chronic neuropathic pain, fibromyalgia, and arthritis.

CBD for Treatment-Resistant Epilepsy
Phase IIIClinical Trial

CBD for Treatment-Resistant Epilepsy

Investigating optimal dosing protocols and long-term outcomes of CBD treatment in pediatric and adult patients with Dravet syndrome and Lennox-Gastaut syndrome.

Cannabinoid Pharmacokinetics Study
OngoingBasic Science

Cannabinoid Pharmacokinetics Study

Comprehensive analysis of how different routes of administration affect cannabinoid absorption, metabolism, and elimination across diverse populations.

Cannabis and Mental Health Outcomes
OngoingEpidemiology

Cannabis and Mental Health Outcomes

Longitudinal study examining the relationship between cannabis use patterns and mental health conditions including anxiety, depression, and psychosis.

Opioid-Sparing Effects of Cannabis
OngoingClinical Trial

Opioid-Sparing Effects of Cannabis

Clinical research investigating whether medical cannabis can reduce opioid requirements in patients with chronic pain and potentially address the opioid crisis.

Cannabis Cultivation & Chemotype Development
OngoingAgricultural Science

Cannabis Cultivation & Chemotype Development

Agricultural research focused on developing standardized cannabis varieties with consistent cannabinoid profiles for medical and research applications.

Recent Publications

Our research published in leading peer-reviewed journals.

Efficacy and Safety of Cannabinoids for Chronic Neuropathic Pain: A Systematic Review and Meta-Analysis

JAMA Network Open (2025)

Mitchell S, Thompson J, Chen R, et al.

Cannabidiol as an Adjunctive Treatment for Pediatric Epilepsy: Long-term Follow-up Results

Lancet Neurology (2025)

Thompson J, O'Brien M, Patel A, et al.

Comparative Pharmacokinetics of Oral, Sublingual, and Inhaled Cannabinoids

Clinical Pharmacology & Therapeutics (2024)

Patel A, Garcia M, Mitchell S, et al.

Cannabis Policy Reform and Public Health Outcomes: An International Analysis

American Journal of Public Health (2024)

Chen R, Garcia M, Thompson J, et al.

The Role of Terpenes in Modulating Cannabinoid Effects: A Review

Frontiers in Pharmacology (2024)

Patel A, Mitchell S, O'Brien M, et al.

Research Methodology

ICRI employs rigorous scientific methods across all research activities. We conduct randomized controlled trials, systematic reviews, meta-analyses, and observational studies following international standards for research excellence.

Our research is guided by principles of transparency, reproducibility, and ethical conduct. All studies undergo review by institutional review boards and are registered in appropriate clinical trial registries.

We collaborate with leading research institutions worldwide and maintain the highest standards of data integrity, patient safety, and scientific rigor.

Scientists conducting cannabis research

Collaborate on Research

Partner with ICRI on groundbreaking cannabis research. We welcome collaborations with academic institutions, healthcare organizations, and research centers worldwide.

Explore Research Partnerships